B cells

January 29, 2016January 29, 2016

Lymphoma Development Linked in Study to Mutations in Gene Regulating Plasma Cells

News

Two studies, published in the journal Nature Immunology, highlight the crucial role of mutations in the Blimp1 gene in lymphoma development. The work centers on plasma cells, or immune cells that develop ... Read more

December 2, 2015December 2, 2015

Lymphoma Study Traces 2 Key Players’ Opposing Roles in B Cell Development

News

In a new study, scientists discovered that two key players in B cells, PI3 Kinase and FOXO1, have opposing roles in controlling B cell proliferation and differentiation in germinal centers, with implications ... Read more

November 20, 2015November 20, 2015

New Genes for B-cell Lymphoma Revealed

News

Novel research has revealed five genes that could predict progression of B-cell lymphoma, three of which had not been identified in previous studies. The work, titled “Novel prognostic genes of diffuse large ... Read more

October 28, 2015October 28, 2015

Lymphoma Patients May Benefit from Discovery of 3,000 New Genes Impacting Immune System

News

Novel findings by UCLA researchers may help immunologists better understand immune cell generation and uncover mechanisms responsible for immune system-related diseases, such as lymphomas. In the study entitled “Long non-coding RNA profiling of human ... Read more

October 26, 2015October 26, 2015

Lymphoma Growth May Be Blocked by Loop That Control’s Enzyme Activity

News

In a new study recently published in the journal Cell and supported by the Leukemia and Lymphoma Society, researchers report a new mechanism regulating gene expression that appears to prevent ... Read more

September 17, 2015September 17, 2015

Long-Term Follow-Up Study Confirms Ibrutinib Effective in Relapsed/Refractory Mantle Cell Lymphoma

News

According to a new report that appeared August 6th in the journal Blood, ibrutinib sustains benefits in people with relapsed or refractory mantle cell lymphoma. The 26.7 month follow-up of a Phase 2 trial of ... Read more

August 7, 2015August 7, 2015

Study Finds Molecule Can Differentiate Immune Cells

News

In a new study entitled “C/EBPα Activates Pre-existing and De Novo Macrophage Enhancers during Induced Pre-B Cell Transdifferentiation and Myelopoiesis” scientists discovered that the transcription factor C/EBPα is the only ... Read more

July 27, 2015July 27, 2015

Personalized Treatment for B cell Lymphoma Patients with Specific ABC Subtype

News

In a new study entitled “Targeting B-Cell Receptor Signaling with Ibrutinib in Diffuse Large B-Cell Lymphoma” a team of researchers identified a subtype of diffuse large B cell lymphoma (DLBCL) ... Read more