Therapeutics

October 20, 2017October 21, 2017

Researchers Identify Enzyme as New Target for Treating Classical Hodgkin’s Lymphoma

News

An enzyme called monoamine oxidase-A (MAO-A) contributes to the growth of classical Hodgkin’s lymphoma cells but not other lymphoma cells, a study reports. It also indicated that a combination of ... Read more

June 23, 2017June 23, 2017

Truxima Shows Similar Safety and Efficacy Results to Rituxan in Phase 3 Trial

News

Results from a Phase 3 trial have shown that Truxima (CT-P10), developed by Celltrion Healthcare, has a similar efficacy and safety profile as Genetech’s Rituxan (rituximab) for the treatment of advanced-stage follicular lymphoma. ... Read more

June 21, 2017

Seattle Genetics Asks FDA to Approve Adcetris for Expanded Set of Lymphoma Patients

News

Seattle Genetics is asking the U.S. Food and Drug Administration to approve Adcetris (brentuximab vedotin) for an expanded set of cutaneous T-cell lymphoma patients. The agency has yet to authorize Adcetris for CTCL. A supplemental Biologics ... Read more

May 10, 2017May 10, 2017

Chest Radiation Therapy Increases Risk of Severe Coronary Artery Disease in Hodgkin Lymphoma Patients

News

A Dutch study found that Hodgkin lymphoma survivors who received chest irradiation are more likely to develop severe coronary artery disease (CAD) 20 years after treatment than those without Hodgkin lymphoma or ... Read more

May 5, 2017May 5, 2017

Mallinckrodt Marks 30 Years of Treating Skin Problems in CTCL Patients Using ECP

News

Extracorporeal photopheresis (ECP) therapy for palliative care of skin manifestations of cutaneous T-cell lymphoma (CTCL) was approved 30 years ago and remains an important therapeutic tool worldwide. Mallinckrodt, the world’s ... Read more

April 21, 2017

Manipulating Select T-cells May Prevent Dangerous Side Effect of Stem Cell Therapy

News

Controlling the balance of two subsets of immune T-cells, known as CD4+ and CD8+, after stem cell transplants makes it possible to prevent graft-versus-host disease (GVHD) while keeping the anti-cancer ... Read more