5 Long-Term and Late Effects for Cancer Survivors


3. Physical Effects of Chemotherapy and Other Drug Therapies


This varies depending on your type of treatment, its length, and your own risk factors, but if you have chemotherapies or other drug therapy, it is possible to experience:

  • Thyroid complications
  • Heart damage/conditions (heart muscle injury, chronic heart failure)
  • Lung damage (inflammation, scarring, acute respiratory distress syndrome, lung failure)
  • Osteoporosis (low bone density)
  • Infertility, including premature menopause or premature ovarian failure in women, and low sperm count and testosterone levels in men
  • Loss of hearing
  • Secondary cancers, such as acute myeloid leukemia and myelodysplastic syndromes
  • Cataracts
  • Impaired immune system function
  • Peripheral neuropathy

Recently, results from a Phase 2 clinical trial demonstrated that mogamulizumab promotes better response rates than standard chemotherapy in patients with adult T-cell leukemia-lymphoma (ATLL).


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